How intrinsic noise affects a pattern-forming mechanism? This has been studied extensively on the reaction-diffusion (RD) equation. Brooks and Bressloff (2016) developed C. elegans synaptic site pattern forming mechanism by introducing a reaction-diffusion-advection (RDA) equation. However, it has been still unknown what is the role of intrinsic fluctuation in the RDA stochastic pattern formation. In the upcoming paper, HK and Bressloff address this question by carrying out a system-size expansion of the RDA master equation.
HK visit the NSF-Simons Center for Multiscale Cell Fate Research (CMCF) at UC Irvine over 6 weeks this summer! Collaboration with Jun Allard and Dae Seok Eom, we are going to study a unique feature of another type of signaling cell protrusions called airinemes.